1. C.elegans is a eukaryotic organism with a genome of 97 Mb and about 20,000 genes. What organizational features of this genome are unusual when compared to the genomes of other eukaryotes, such as yeast and Drosophila? (2)
2. Indicate the inheritance pattern, genomic location and mutation in any two diseases caused by single gene mutations which follow mendelian inheritance. Also, specify the genomic location in any two diseases resulting from gene polymorphisms with complex inheritance. (5)
3. What are SNPs?Explain the relevance of studying these citing any two of their important applications.(3)
4. Gene Prediction by computers is different from number of genes identified by experimental methods. Why is it so? Is there any correlation between the complexity of an organism and the total number of genes in its genome? Justify. (3)
5. Define SNPs. Describe a possible use of this technique in medicine. How do the physicians decide our susceptibility or resistance to a particular disease through this technique ? Explain with the help of an example. (5)
6. Define the term genome and genomics. (2)
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