1. Explain how cDNA microarray technique can be used to study cellular response to the environment? support your answer with the help of a flowchart. (5)
2. Number of genes is not related to the number of proteins. Justify. (3)
3. CML patients have the ‘Philadelphia Chromosome”. How is this chromosome detected? Explain the technique with a diagram. He has been put on a combination drug therapy for the past 2 months How can this technique be used to monitor the effect of chemotherapy? (5)
4. With the help of a flowchart show different types of proteomics and the scientific knowledge that can be gained from them. Also explain the main types of proteomics.(5)
5. What is a proteome? Why it is termed that proteome of a given cell is dynamic?(2)
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