A DNA library is a collection of DNA fragments that have been cloned into vectors so that researchers can identify and isolate the DNA fragments that interest them for further study. There are basically two kinds of libraries: genomic DNA and cDNA libraries.
A genomic library is a collection of the total genomic DNA from a single organism. The DNA is stored in a population of identical vectors, each containing a different insert of DNA.
One more representation;
A cDNA library is a combination of cloned cDNA (complementary DNA) fragments inserted into a collection of host cells.
Now the question arises what is cDNA and how it is constructed:
Here, we have used reverse transcriptase. In class XI we have studied about this enzyme which construct DNA against mRNA strand. Thus cDNA is constructed. Now we have to construct a cDNA library:
One more representation of cDNA library:
COMPARATIVE STUDY OF GENOMIC AND cDNA LIBRARY:
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